The 10-Tier Longevity Protocol
The clinical framework behind Rebel Health — designed by our CMO Dr. Alec Weir and a team of board-certified physicians. Not a 90-day program. A sequential, lifelong arc you climb at your own pace.
Build the foundation, fortify the structure, reach the summit, maintain the view. Every tier builds on the one before it — you never skip ahead.
You don't sprint to the summit. You build a foundation, fortify the structure, reach the summit, and then maintain the view. The protocol moves in tiers because the body does — a peptide prescribed without understanding your metabolic and inflammatory baseline is a shot in the dark. On a solid foundation, it's a calculated intervention within a coordinated system.
That's the whole idea: sequential, patient-paced, and never skipping ahead. Your physician, dietitian, and strength coach work from one integrated plan, not five separate ones.
Everything starts with metabolic health.
Insulin sensitivity, cardiovascular risk, metabolism, and the coaching fundamentals. Comprehensive metabolic panels, body composition by DEXA, and an integrated training + nutrition plan built from your own data.
Early detection, years before conventional screening would look — including advanced options like the Galleri multi-cancer blood test where clinically appropriate. The earlier you find it, the more treatable it is.
Go cellular, then protect what matters most.
Your cells' energy system. Physician-guided support for NAD+ pathways and mitochondrial function — because declining cellular energy is one of the recognized hallmarks of aging.
Short amino-acid chains that signal specific biological processes — used for healing, recovery, and cognition (e.g., BPC-157). At Rebel, peptides are never prescribed in isolation; they're layered onto a solid metabolic and cellular base.
A brain-health baseline and cognitive monitoring, integrated with the metabolic and cardiovascular data from earlier tiers. Brain health isn't separate from the rest of the body — which is exactly why you don't skip ahead.
A complete, systems-level picture — and the frontier.
A full organ sweep — liver, kidney, thyroid, adrenals, heart, lungs — evaluated for suboptimal function, not just disease. Advanced imaging such as coronary calcium scoring where indicated.
Biomechanical assessment, injury prevention, and joint care — including regenerative injections where clinically appropriate — in lockstep with the strength program that's been running since Tier 1.
Evidence-informed pharmacology such as mTOR inhibition (rapamycin) and senescent-cell clearance, introduced only after the foundation is solid — with physician safety protocols, not biohacking.
The frontier. Emerging interventions with strong early evidence, evaluated case by case for members who've built a complete foundation across every prior tier.
The summit isn't the end. It's the new baseline.
Lifelong optimization — annual comprehensive panels, DunedinPACE epigenetic pace-of-aging testing, ongoing protocol adjustments, and continuous coordination across your whole team. Active surveillance, not a snapshot once a year.
Hormone optimization and your strength & nutrition coaching aren't a single step — they run throughout the protocol, tuned to your bloodwork and goals as you progress. Hormones are evaluated and optimized under physician supervision as part of your foundation, then revisited at every tier.
This is evidence-based medicine administered by board-certified physicians within a structured framework — not a supplement stack off the internet. The sequence exists for a reason, and so do the guardrails.
Tiers are introduced as you're ready. Some members spend a year in the foundation; others move faster. It's your climb.
Examples: pre-cycle blood counts before senolytics, and holding certain medications during infections or before surgery.
Bloodwork, DEXA, imaging, Galleri and epigenetic testing are ordered at transparent cash-pay rates — not bundled into the membership fee.
Your physician, dietitian, and strength coach share the same channel and the same plan, so interventions reinforce each other.
This page is educational and is not medical advice. The 10-Tier Longevity Protocol is a clinical framework; specific tests, medications, peptides, and therapies are prescribed individually by a licensed physician only where clinically appropriate for a given patient, and are not guaranteed to any member. Tier progression is determined by your physician.
Therapies named here are illustrative examples of interventions that may be used within a tier — they describe the category, not a promised treatment plan. Some interventions are emerging and used off-label under physician supervision.
Diagnostics are cash-pay add-ons, offered at transparent rates and not included in the membership fee. Rebel Health Alliance is a direct primary care and health-optimization membership; it is not health insurance.
The 10-tier protocol is the engine inside Rebel Health and Rebel Peak. Pick the level that fits you — or talk to us first about where you'd start.